GC KOLONLARI ve AKSESUARLARI
Thermosorb-NEllutia GC KOLONLARI ve AKSESUARLARI
Scientists have long been aware that amines can react with various nitrosating agents, under a variety of conditions to form a wide array of N-nitroso derivatives.
Airborne Nitrosamine Monitoring
Scientists have long been aware that amines can react with various nitrosating agents, under a variety of conditions to form a wide array of N-nitroso derivatives. Amines can also be transnitrosated with already formed N-nitroso or C-nitro compounds via a transnitrosation reaction. In view of all the various pathways for nitrosation of the amine and amine derivatives it is not unexpected that N-nitroso compounds are found in many different areas of the environment. Whilst it is known that nitrosamine are potent carcinogens and may represent a carcinogenic exposure which most people experience on a daily basis, the determination of that exposure is extremely questionable because of the formation of artifacts.
Determination of airborne nitrosamines have been prone to artifact formation (false positives, if solid sorbents are used, and sample loss, i.e., false negatives dues to desorption or degradation in solver if wet traps are used). Nitrosamines are also known to degrade in UV light.
The Ellutia Thermosorb-N offers a method for collecting airborne nitrosamines which overcomes the problems with false positive and false negative results.
Nitrogen oxides can easily react with amines to form nitrosamines. The ease of this reaction suggests that nitrosamines can be artifactually formed either during collection or analysis. To avoid this formation, Thermosorb-N air samplers contain an artifact trap that includes an amine-trapping agent and a nitrosation inhibitor. Nitrosamine levels determined from a sample collected using the Thermosorb-N air sampler, are representative of airborne nitrosamine levels.
In addition to artifact formation, another problem with other collection techniques involved ultraviolet (UV) light degradation of the collected nitrosamines and desorption of the sample over time or temperature. Thermosorb-N air samplers are made of an opaque plastic and employ solid sorbent materials to ensure the sample is not lost.